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Collagen · Moderate evidence

What collagen is for and when to take it

The short answer. The first thing to know about collagen is what it is not: it is not a protein for muscle. It lacks essential amino acids, has no tryptophan and very little leucine, so it does not count towards your daily protein however much the label says 90 % protein. Where there is a signal is in connective tissue: tendon, ligament and cartilage. And there timing really matters, which is rare in supplements.

There are studies in favour, but few, with small samples or measuring markers instead of outcomes. No figure on this page is attributed to a specific product: the effect belongs to the ingredient and every number carries its source next to it.

01 What it does and how much

Each row is a measured effect, with the figure the study gives and the source number. Where the evidence gives no figure, the column says so instead of making up a percentage.

Effects of collagen with their source
EffectHow muchDetail
Collagen synthesis (PINP marker in blood)x2Fifteen grams of gelatin with vitamin C, an hour before a short bout of activity, doubled the collagen synthesis marker versus control. It is a blood marker, not a measured tendon: the signal is promising, not proof of a clinical outcome. [1]
Joint pain in athletesimprovement versus placeboWith 10 g a day of hydrolysed collagen for 24 weeks in athletes with activity-related joint pain. Note the duration: six months, not two weeks. [2]
As protein for muscledoes not countIncomplete amino acid profile: no tryptophan and very little leucine, which is what triggers muscle synthesis. Adding it to your daily protein is fooling yourself in the count. [3]
Vitamin CneededVitamin C is a cofactor of the enzymes that make collagen. It is included in the study, which is why many products carry it: without it the protocol is not the same. [1]

02 How to take it

  • Dose. 10 to 15 g of hydrolysed collagen or gelatin, with about 50 mg of vitamin C.
  • When. Around an hour before loading the tissue (training, rehab). It is one of the few supplements where timing has a physiological reason: blood reaches the tendon during exercise.
  • How long before you notice it. Weeks to months. The joint pain study lasted 24 weeks.

Details that change the result

  • Type I, II or marine makes no difference: there is no solid evidence that one beats another for this use. What has been studied is the grams and the timing.
  • Ordinary gelatin works and costs a fraction. Hydrolysed collagen dissolves in cold liquid and tastes of less, which is what you pay for.
  • Do not add it to your daily protein. If you take 15 g of collagen and count it, you are 15 g short of real protein.
  • For skin and nails there are studies, but many are funded by manufacturers and use soft measures. This page sticks to sport.

03 When it makes sense and when it does not

Worth it if

  • Tendinopathies or recurring load-related joint discomfort.
  • Impact or high-volume sports: running, jumping, racket sports.
  • Returning after a connective tissue injury, as support for rehab.

Not worth it if

  • As a protein source to gain muscle. For that it is one of the worst options there is.
  • Expecting an effect within weeks: the studies that find something last months.
  • If the joint pain is new, severe or limits movement. That needs checking, not supplementing.

04 Sources

Every figure above comes from here. They are position stands from scientific societies, meta-analyses and peer-reviewed reviews: if a claim cannot hang from one of these lines, it is not on the page. References are cited in their original form.

  1. Shaw G et al. Vitamin C-enriched gelatin supplementation before intermittent activity augments collagen synthesis. Am J Clin Nutr. 2017;105(1):136-143. 15 g de gelatina con vitamina C una hora antes del ejercicio. doi:10.3945/ajcn.116.138594
  2. Clark KL et al. 24-week study on the use of collagen hydrolysate as a dietary supplement in athletes with activity-related joint pain. Curr Med Res Opin. 2008;24(5):1485-96. 10 g diarios durante 24 semanas. doi:10.1185/030079908X291967
  3. Jager R et al. ISSN position stand: protein and exercise. J Int Soc Sports Nutr. 2017;14:20. La calidad de una proteina depende de que aporte los nueve aminoacidos esenciales y suficiente leucina. doi:10.1186/s12970-017-0177-8

This is not medical advice. It is what some studies say about an ingredient, not a protocol for you. With an illness, medication or pregnancy involved, the decision belongs to a healthcare professional who knows you.

Questions about collagen

Answered with the data on this page

Does collagen count as protein?
Not for muscle. Its amino acid profile is incomplete: no tryptophan and very little leucine, which is what triggers muscle synthesis. Even if the label says 90 % protein, it should not be added to the daily total you aim for to build muscle.
When should you take collagen?
Around an hour before training, with vitamin C. It is one of the few supplements where timing has a physiological reason: connective tissue gets more blood during exercise, so you want the amino acids circulating right then.
How much collagen should you take a day?
Between 10 and 15 g. The joint pain study in athletes used 10 g a day for 24 weeks, and the collagen synthesis study used 15 g of gelatin with vitamin C an hour before exercise.
Is marine or bovine collagen better?
There is no solid evidence that one beats the other for tendons and joints. What has been studied is the grams, the vitamin C and the timing, not the source animal. Choosing on price per gram is reasonable.
Does ordinary gelatin work instead of hydrolysed collagen?
The study that doubled the synthesis marker used gelatin. The practical difference is that hydrolysed collagen dissolves in cold liquid while gelatin sets: it is convenience, not efficacy.

And now, which to buy

Prices, kept apart from the evidence

This page explains what collagen does and deliberately names no brand. The comparison is the other half: 168 products from 16 stores from €20.82 per kg, sorted by price and by how verifiable their certification is.

See the collagen comparison

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